Is the Hail Mary Prayer Biblical? Examining It Line by Line. The Hail Mary is one of the best-known prayers in Roman Catholicism. It combines language drawn from Luke’s Gospel with later statements asking Mary to intercede for sinners: “Hail Mary, full of grace, the Lord is with thee. Blessed art thou among women, and blessed is the fruit of thy womb, Jesus. Holy Mary, Mother of God, pray for us sinners, now and at the hour of our death.”